Description
Genomics, Proteomics, and Cell Biology are interconnected fields studying life’s molecular basis: Genomics maps the DNA blueprint (genome), Proteomics studies the dynamic, functional proteins (proteome) built from genes, and Cell Biology examines the cell’s structure and processes, showing how genes direct protein production, which then perform cell functions, offering a complete picture from code to machinery to action in health and disease. This book will provide an overview of interconnected fields bioinformatics subjects and discuss some of the ideas behind the approaches and tackle some common tasks.
About the Author
Prof. (Dr) P. Shanmughavel,Ph D., D.Sc.Adjunct Faculty (ICMR-NIRT),Former Professor of Bioinformatics, Dept. of Botany, Bharathiar University, Coimbatore has 30 years of research and 20 years of teaching experience in Bioinformatics. Published 130 research papers and 21 books. Successfully carried out several research projects and a founder of DBT Bioinformatics Centre at Bharathiar University. Won many National/International Awards, mentored 30 PhD scholars, visited several countries.
Dr. Luke Elizabeth Hanna, Scientist-F, Head Department of Virology and Biotechnology, ICMR-NIRT, Chennai. Published over 140 research articles and 7 book chapters, presented several research findings in National/International conferences/meetings. Established a large TB Biorepository at medical college level viral research and diagnostic laboratory at ICMR-NIRT. Won several awards & mentored 12 PhD students, 6 post-doctoral research fellows.
Contents
- Annotation of the Genome1
- Gene Prediction4
- Genome Analysis15
- Functional Genomics25
- Expressed Sequence Tag31
- Expression and Regulation of Entire Set of Genes51
- Comparative Genomics70
- Principles of Protein Classification82
- Proteome Analysis97
- SDS-PAGE125
- Visualization132
- Visualization of the Blotted Proteins by Coomassie Blue Staining138
- Microcharacterization of Protein Spots142
- Cell149
- Cell Organelles and their Functions155
- Cell Membrane Structure and Transport Proteins178
- Mechanisms of Transport184
- Carbohydrates189
- Proteins193
- Lipids200
- Nucleic Acids207
- Cell Energetics212
- Utilization of Glucose, Fat and Protein218
- Enzymes221
- Michaelis-Menten kinetics227
- Mechanism of Enzyme Action234
- Cell Cycle239
- Meiosis249
- DNA Replication255
- DNA Transcription263
- Translation267
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